Transport according to GARP: receiving retrograde cargo at the trans-Golgi network
نویسندگان
چکیده
منابع مشابه
The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network.
Retrograde transport pathways from early/recycling endosomes to the trans-Golgi network (TGN) are poorly defined. We have investigated the role of TGN golgins in retrograde trafficking. Of the four TGN golgins, p230/golgin-245, golgin-97, GCC185, and GCC88, we show that GCC88 defines a retrograde transport pathway from early endosomes to the TGN. Depletion of GCC88 in HeLa cells by interference...
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ژورنال
عنوان ژورنال: Trends in Cell Biology
سال: 2011
ISSN: 0962-8924
DOI: 10.1016/j.tcb.2010.11.003